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Estee Lauder Time Zone Anti-Line and Wrinkle Creme is developed with an exclusive Sirtuin EX1 Technology and TriHyaluronic Complex, which helps counteract premature skin ageing and rejuvenates the skin by significantly reducing visible wrinkles, unveiling softer, sleeker and brighter skin. Ideal for normal or combination skin types. Dermatologist tested. Non-acnegenic.