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The price will be the main issue with people looking to sample adobe software- when you're spending more than £300 on a product you're expected to know why you're buying it. So the people reading this review will already be converted, as there is no real strong commercial alternative to the adobe products now that quark is all but dead in the water!
It is complicated to use, slightly illogical and doesn't work seamlessly with other adobe products (some keyboard shortcuts do completely different things) so don't think you can jump straight into this just because you know photoshop.
If you are willing to put in the time to learn it then indesign is powerful software capable of creating pro standard work. It's difficult to really explain what the software does, but it's a 'desktop publishing suite', which means you can design anything for web/print, I have used it to design leaflets, posters, business cards, catalogues and general graphic design things. You can do some of the design work in indesign but it's mainly for layout- so create the graphics in other programs such as photoshop and then layout in indesign.
This is specialist software that not many people who don't work in graphic design can justify purchasing, but if you think you can earn money doing design work there is no better program for content creation.