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Glanzmann Thrombastenia

Description: A rare congenital abnormality of blood platelets, characterized by easy bruising and excessive bleeding after trauma ... more

Glanzmann Thrombastenia ... and epistaxis. The platelet membrane lacks specific glycoproteins Iib and IIIa which are the receptor of fibrinogen. Bleeding is prologed, clot retraction is diminished, and platelets do not aggregate during blood coagulation or after addition of ADP (adenosine diphosphate).
Also known as: Glanzmann's syndrome, Glanzmann-Nägeli syndrome, Nägeli syndrome II, Révol's syndrome.

Newest Review: ... symptoms that occur as children get older are petechial spots, bleeding from the gums and heavy periods can be a problem for girls. Petechial spots are small red marks on the skin that indicate bleeding below the surface, similar to a bruise but on a smaller scale. Muscle injuries have to be dealt with carefully as sometimes they can bleed into joints and that can be severe. Obviously any ... more

... type of surgery can also be life threatening and the most simple procedures have to be done with extra care. It has been said that the condition isn't so bad as the sufferer gets older but this could be due to many factors such as being more careful ...more

Read Reviews for Glanzmann Thrombastenia

Glanzmann Thrombastenia: A Rare Blood Disorder (2236 words)
by - written on 09/04/06 (Very useful, 1265 readings)
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My life began almost 36 years ago and I was brought up in a two-bedroom council flat with my mum and dad who will celebrate their 40th wedding anniversary next year. I am an only child as my mum had a major health problem - namely Glanzmann's Thrombasthenia, or GT, which is a platelet disorder and means that she is a bleeder. This tends to happen through nosebleeds or her gums bleeding but obviously childbirth can have its problems too. She has had many visits in hospitals over the years and even a simple scale and polish of her teeth requires preventative treatment for bleeding before it's carried out. My mum is a real star to have handled all this in her ... Read the complete review

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