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I now own two of these great Asus mo-boards. Yep, good enough to buy a second one. Win7 64 bit installation on both went very well. Admittedly, I had some driver update issues building out the first one last year, but the latest build in January (from Amazon)came with "current enough" drivers on the CD for good performance and functionality. Of course, I updated to the latest drivers with Windows Update. That seemed to go just fine.
The Win7 experience numbers are impressive with stock configuration, with one exception: Graphics performance significantly lags behind the rest of the system components in my AMD Phenon II X4 with 4gig memory configuration. I'm not a gamer, so it works for me. (is there an emoticon I should insert here for the standard "YMMV" disclaimer?) But, please note that the onboard graphics fully supports my new Blu-ray burner/player output on the hdmi port at 1080p. That rocks!
I have not been able to test the USB3 functionality yet. I stress tested both boards using Prime 95 overnight without error. My first build had an issue due to infantile failure of some Corsair memory, but that was fixed by warranty memory replacement.
I see very good behavior with Win7's power conservation features. The only warning I can provide is that one should not plan on carrying over older internal devices. My very old (just 6 years!) DVD drive caused me some fun and games, but I'm almost certain that was an OS issue as opposed to motherboard support.