Possibly one of the weirdest Sh'mups you're ever likely to play, certainly the most customisable, Blast Works is a true indie title, one that grew up on PC and was reworked for the Wii.
Imagine you're a block of Lego (As you do) and everything you walk into sticks to your brick like form, firing out bullets in whatever angle it stuck to you. Now imagine you're a flying Lego brick, and those things you're walking into are evil flying bricks from some sort of brick dimension, and the only way to kill them is to attach them to yourself.
Now what sounds like some sort of perverted acid scenario turns about to be a fantastic little shooter. Rather than collect power ups to increase your fire power, you collect enemies. Shoot them and they'll become harmless, move into them while in their harmless state and they'll attach to your ship. Depending on the angle you "capture them" depends on where your extra "gun" will be. By the end of the first level, you'll take up 90% of the screen like some hideous mess of... Lego.
Throw in an editor that allows you to recreate every visual aspect of the game, as well as the ability to trade online with your pals and you've got something not only different, but decidedly decent to boot.