The Guinness Brewery can easily be reached in Dublin as both the green and red sightseeing hop on hop off buses stop there on their tour of the city. It costs 15 euro per adult to enter but if you buy online you will get a 10% discount. This is quite a popular attraction and we went early to avoid the crowds. Note, this isn't the actual real brewery now so you wont see any brewing. On the ground floor is a rather vast gift shop where you can buy almost anything endorsed by Guinness though it isn't cheap. The brewery itself has many many floors which brief you on the history of Guinness. You will learn about how the brewery was first created, how Guinness is made and the processes involved in making the black stuff. Further on up you get to learn about the numerous Guinness advertisements made over the years as well as all the different variations of drink that have been made. There are lots of multimedia tools designed to help the visitor learn and understand what it is that they are seeing.
The real treat though is the gravity bar at the top of the building. You get a 360 degree panoramic view of Dublin and can see all the sights of the city. What's more you get a free pint of Guinness when you're there!
There are lifts and escalators so it is quite disabled friendly. Allow at least a couple of hours for the tour.