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I bought the Asus MX279H monitor when I decorated my study last summer and it is a lovely piece of equipment. I was unsure about whether I could justify the extra cost against other 27 inch monitors but it is well worth the additional cost.
Broadcasting in Full 1080p HD, the picture quality from the MX279H is second to none. You can connect to your PC using the HD to DVI cable (or HDMI to HDMI if you prefer not to use the cable provided) or VGA. Personally, I don't see why anyone would use VGA these days as this is old technology.
Although the display of the monitor is huge, the actual space this will take up on your desk is very minimal. The thickness of the monitor is no more than a centimetre and, as long as you have enough space, width-ways, this monitor will look a picture on anyones desk.
Before buying this monitor, I did consider buying a second smaller monitor rather than one big monitor. With hindsight, I believe I made the right decision as I have more control over where I position things on one screen. What I do like about the Asus is that I can now multitask easier than ever before. I am a big sports fan so this monitor now allows me to have a web browser open for approximately 75% of the screen and then in the final quarter, I can open another two web browser instances to show me two separate TV channels (normally Sky Sports 1 and 2 in my case). This monitor is also brilliant for when I play poker as I can have multiple tables open and view them all perfectly, rather than having them all squashed to a small size.
In conclusion, I would have no hesitation in recommending this monitor to anyone who is looking to upgrade. You can get cheaper ones on the market but the resolution and picture quality will be considerably lower than that of the Asus. With monitors, you certainly do get what you pay for and Asus have come up with a real gem with the Ms279H.